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PEPSE Assessment

Do you need to talk to someone about PEPSE?

What is PEPSE?

  • This is a 28 day course of tablets that can prevent HIV if you have been at risk.
  • It needs to be started within 72 Hours (3 days) of a risk happening.
  • It is only considered for people who have had condom break or unprotected sex with someone who is HIV positive.
  • There are National Guidelines that we use when considering if someone needs to start this treatment.

The following tool will help you decide if you should talk to someone about PEPSE

Have you had unprotected sex?

Sex without a condom or where the condom broke or slipped off

When used properly and consistently condoms are very effective at preventing STI and HIV transmission. For further information on STIs and HIV please see our relevant pages, STIs and Testing information, HIV information

Have you had unprotected sex in the last 72 hours?

PEPSE need to be started within 72 hours (3 days) or a risk happening. You may have been exposed to HIV, in some cases a months’ worth of treatment can be used to prevent you becoming HIV Positive from this episode. Please see here for information on what you need to do “what is PEPSE”. Females should consider risk of pregnancy and contraception.

Is the person you had sex with HIV positive?

You have indicated that you may have been exposed to HIV, in some cases a months’ worth of treatment can be used to prevent you becoming HIV Positive from this episode. Please see here for information on what you need to do “what is PEPSE

If you have had unprotected sex you should still consider STI and HIV testing. Some people may also benefit from certain vaccinations. Females should consider risk of pregnancy and contraception.

Locate a confidential service

Find your local Pharmacy or Clinic and book a confidential appointment.


Order a testing kit

Worried about STIs or other sexual health problems? You can request a confidential free home testing kit.

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